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1

cis -4-Amino- l -proline Residue As a Scaffold for the Synthesis of Cyclic and Linear Endomorphin-2 Analogues: Part 2

Mollica, Adriano, Pinnen, Francesco, Stefanucci, Azzurra, Mannina, Luisa, Sobolev, Anatoly P., Lucente, Gino, Davis, Peg, Lai, Josephine, Ma, Shou-Wu, Porreca, Frank, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 524 KB

english, 2012

2

Pseudopeptides Containing Isothiazolidine-1,1-dioxide-3-carboxylic Acid: Synthesis and Properties of (S)-Isothiazolidine-1,1-dioxide-3-carboxylic Acid, a New γ - Sultam Analogue of Pyroglutamic Acid

Grazia Luisi, Francesco Pinnen

Journal:

Archiv der Pharmazie

Year:

1993

Language:

english

File:

PDF, 320 KB

english, 1993

3

Synthesis and Activity of the Glutathione Analogue γ-(L-γ-Oxaglutamyl)-L-cysteinyl-glycine

Anna Calcagni, Silvestro Duprè, Gino Lucente, Grazia Luisi, Francesco Pinnen, Domenico Rossi, Alessandra Spirito

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 468 KB

english, 1996

4

Ibuprofen and Glutathione Conjugate as a Potential Therapeutic Agent for Treating Alzheimer's Disease

Francesco Pinnen, Piera Sozio, Ivana Cacciatore, Catia Cornacchia, Adriano Mollica, Antonio Iannitelli, Eleonora D′Aurizio, Amelia Cataldi, Susi Zara, Cinzia Nasuti, Antonio Di Stefano

Journal:

Archiv der Pharmazie

Year:

2011

Language:

english

File:

PDF, 490 KB

english, 2011

5

Bicyclic peptides: Solution conformation and Ca2+ binding of the heterodetic bicyclic decapeptide cyclo(Glu1-Leu2-Pro3-Gly4-Ser5-Ile6-Pro7-Ala8)-cyclo(1γ → 5β) Phe9-Gly10

Giancarlo Zanotti, Francesco Pinnen, Gino Lucente, Livio Paolillo, Gabriella D'Auria, Enrico Trivellone, Maria D'Alagni

Journal:

Year:

1989

Language:

english

File:

PDF, 750 KB

english, 1989

6

ChemInform Abstract: Design and Synthesis of Glutathione Analogues

Gino Lucente, Grazia Luisi, Francesco Pinnen

Journal:

Year:

1999

File:

PDF, 23 KB

1999

7

ChemInform Abstract: Ψ(SO2NH) Transition State Isosteres of Peptides. Synthesis and Bioactivity of Sulfonamido Pseudopeptides (V) Related to Carnosine.

Anna Calcagni, Pier Giuseppe Ciattini, Antonio Di Stefano, Silvestro Dupre, Grazia Luisi, Francesco Pinnen, Domenico Rossi, Alessandra Spirito

Journal:

Year:

2000

File:

PDF, 31 KB

2000

8

ChemInform Abstract: 4-Amino-1,2-dithiolane-4-carboxylic Acid (Adt) as Cysteine Conformationally Restricted Analogue. Synthetic Protocol for Adt Containing Peptides.

Enrico Morera, Marianna Nalli, Francesco Pinnen, Domenico Rossi, Gino Lucente

Journal:

Year:

2000

File:

PDF, 34 KB

2000

9

Asymmetric hydrogenation of β - methylcinnamates of phenylalkylmethanols. Catalyst-phenyl groups interactions in the preferred adsorption conformation

Carlo Gallina, Gino Lucente, Francesco Pinnen

Journal:

Year:

1978

Language:

english

File:

PDF, 278 KB

english, 1978

10

Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold: Synthesis and bioactivity

Domenica Torino, Adriano Mollica, Francesco Pinnen, Federica Feliciani, Susanna Spisani, Gino Lucente

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 260 KB

english, 2009

11

Synthesis and evaluation of new endomorphin analogues modified at the Pro2 residue

Domenica Torino, Adriano Mollica, Francesco Pinnen, Gino Lucente, Federica Feliciani, Peg Davis, Josephine Lai, Shou-Wu Ma, Frank Porreca, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 292 KB

english, 2009

12

Facile transformation of glutamic acid into proline residue inside a tripeptide backbone

Adriano Mollica, Azzurra Stefanucci, Federica Feliciani, Domenica Torino, Ivana Cacciatore, Francesco Pinnen, Gino Lucente

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 206 KB

english, 2010

13

Synthesis of (S)-5,6-dibromo-tryptophan derivatives as building blocks for peptide chemistry

Adriano Mollica, Azzurra Stefanucci, Federica Feliciani, Gino Lucente, Francesco Pinnen

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 205 KB

english, 2011

14

ψ(SO2-NH) transition state isosteres of peptides. Synthesis of the glutathione disulfide analogue

Grazia Luisi, Anna Calcagni, Francesco Pinnen

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 176 KB

english, 1993

15

Cyclization of activated N-benzyloxycarbonyl-tripeptides

Gino Lucente, Francesco Pinnen, Giancarlo Zanotti

Journal:

Tetrahedron Letters

Year:

1978

Language:

english

File:

PDF, 290 KB

english, 1978

16

A new method for oxidative decarboxylation of N-acyl-α-amino-acids and peptides

Gino Lucente, Francesco Pinnen, Giancarlo Zanotti

Journal:

Tetrahedron Letters

Year:

1978

Language:

english

File:

PDF, 303 KB

english, 1978

17

Synthesis and biological evaluation of the disulfide form of the glutathione analogue γ-(l-glutamyl)-l-cysteinyl-l-aspartyl-l-cysteine

Ivana Cacciatore, Antonio Di Stefano, Silvestro Duprè, Enrico Morera, Francesco Pinnen, Alessandra Spirito

Journal:

Bioorganic Chemistry

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

18

4-Amino-1,2-dithiolane-4-carboxylic acid (Adt) as cysteine conformationally restricted analogue. synthetic protocol for Adt containing peptides

Enrico Morera, Marianna Nalli, Francesco Pinnen, Domenico Rossi, Gino Lucente

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

19

Proline–Glutamate Chimeras in Isopeptides. Synthesis and Biological Evaluation of Conformationally Restricted Glutathione Analogues

Mario Paglialunga Paradisi, Adriano Mollica, Ivana Cacciatore, Antonio Di Stefano, Francesco Pinnen, Anna Maria Caccuri, Giorgio Ricci, Silvestro Duprè, Alessandra Spirito, Gino Lucente

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

20

Transition state isosteres of the γ-glutamyl peptide bond hydrolysis: synthesis and characterization of the ψ[CH2NH] pseudopeptide analogue of glutathione

Ivana Cacciatore, Antonio Di Stefano, Grazia Luisi, Francesco Pinnen, Piera Sozio

Journal:

Journal of Peptide Science

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

21

New potent biphalin analogues containingp-fluoro-l-phenylalanine at the 4,4′ positions and non-hydrazine linkers

Adriano Mollica, Francesco Pinnen, Federica Feliciani, Azzurra Stefanucci, Gino Lucente, Peg Davis, Frank Porreca, Shou-Wu Ma, Josephine Lai, Victor J. Hruby

Journal:

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

22

CNS delivery ofl-dopa by a new hybrid glutathione–methionine peptidomimetic prodrug

Francesco Pinnen, Ivana Cacciatore, Catia Cornacchia, Adriano Mollica, Piera Sozio, Laura S. Cerasa, Antonio Iannitelli, Antonella Fontana, Cinzia Nasuti, Antonio Di Stefano

Journal:

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

23

Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2

Cesare Giordano, Anna Sansone, Annalisa Masi, Gino Lucente, Pasqualina Punzi, Adriano Mollica, Francesco Pinnen, Federica Feliciani, Ivana Cacciatore, Peg Davis, Josephine Lai, Shou-Wu Ma, Frank Porre

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 379 KB

english, 2010

24

Structural elucidation of the oxidation product of aminoethylcysteine ketimine decarboxylated dimer by peroxynitrite

Luisa Mannina, Stéphane Viel, Silvestro Duprè, Laura Pecci, Mario Fontana, Francesco Pinnen, Antonio Antonucci, Anna Laura Segre

Journal:

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

25

ChemInform Abstract: Ytterbium Triflate Catalyzed Meerwein—Ponndorf—Verley (MPV) Reduction.

Adriano Mollica, Salvatore Genovese, Francesco Pinnen, Azzurra Stefanucci, Massimo Curini, Francesco Epifano

Journal:

Year:

2012

File:

PDF, 27 KB

2012

26

ChemInform Abstract: Synthesis and Bioactivity of Secondary Metabolites from Marine Sponges Containing Dibrominated Indolic Systems

Adriano Mollica, Marcello Locatelli, Azzurra Stefanucci, Francesco Pinnen

Journal:

Year:

2012

File:

PDF, 18 KB

2012

27

Synthesis and biological evaluation of new active For-Met-Leu-Phe-OMe analogues containing para-substituted Phe residues

Adriano Mollica, Federica Feliciani, Azzurra Stefanucci, Roberto Costante, Gino Lucente, Francesco Pinnen, Daniela Notaristefano, Susanna Spisani

Journal:

Journal of Peptide Science

Year:

2012

Language:

english

File:

PDF, 543 KB

english, 2012

28

Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues

Leonardo Baldassarre, Francesco Pinnen, Catia Cornacchia, Erika Fornasari, Luigina Cellini, Marina Baffoni, Ivana Cacciatore

Journal:

Journal of Peptide Science

Year:

2012

Language:

english

File:

PDF, 795 KB

english, 2012

29

N-Acetyl-L-Methionyl-L-Dopa-Methyl Ester as a dual acting drug that relieves L-Dopa-induced oxidative toxicity

Alba Minelli, Carmela Conte, Elvira Prudenzi, Ivana Cacciatore, Catia Cornacchia, Elena Taha, Francesco Pinnen

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 958 KB

english, 2010

30

Evaluation of rat striatal l-dopa and DA concentration after intraperitoneal administration of l-dopa prodrugs in liposomal formulations

Antonio Di Stefano, Maria Carafa, Piera Sozio, Francesco Pinnen, Daniela Braghiroli, Giustino Orlando, Giuseppe Cannazza, Massimo Ricciutelli, Carlotta Marianecci, Eleonora Santucci

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

31

Ytterbium triflate catalysed Meerwein–Ponndorf–Verley (MPV) reduction

Adriano Mollica, Salvatore Genovese, Francesco Pinnen, Azzurra Stefanucci, Massimo Curini, Francesco Epifano

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

32

Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands

Antonio Di Stefano, Piera Sozio, Grazia Luisi, Ivana Cacciatore, Barbara Mosciatti, Barbara Costa, Antonio Lucacchini, Claudia Martini, Francesco Pinnen

Journal:

Year:

2002

Language:

english

File:

PDF, 288 KB

english, 2002

33

Design and synthesis of glutathione analogues

Gino Lucente, Grazia Luisi, Francesco Pinnen

Journal:

Year:

1998

Language:

english

File:

PDF, 328 KB

english, 1998

34

Ψ(SO2NH) transition state isosteres of peptides. Synthesis and bioactivity of sulfonamido pseudopeptides related to carnosine

Anna Calcagni, Pier Giuseppe Ciattini, Antonio Di Stefano, Silvestro Duprè, Grazia Luisi, Francesco Pinnen, Domenico Rossi, Alessandra Spirito

Journal:

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

35

Cyclols, cyclodepsipeptides, and N-acyl-diketopiperazines from linear precursors: Synthesis and crystal structure of 10-membered cyclodepsipeptides

GIANCARLO ZANOTTI, FRANCESCO PINNEN, GINO LUCENTE, SILVIO CERRINI, ENRICO GAVUZZO, FERNANDO MAZZA

Journal:

Chemical Biology & Drug Design

Year:

1983

Language:

english

File:

PDF, 657 KB

english, 1983

36

N-acyl-diketopiperazines. : Crystal structure and conformation of N-(N-phenylacetyl-L-alanyl)-cyclo-(L-phenylalanyl-D-prolyl)*

Silvio Cerrini, Walter Fedeli, Gino Lucente, Fernando Mazza, Francesco Pinnen, GIancarlo Zanotti

Journal:

Chemical Biology & Drug Design

Year:

1984

Language:

english

File:

PDF, 435 KB

english, 1984

37

Cyclization under mild conditions of anthraniloyl- and N-methyl-anthraniloyl dipeptides

FRANCESCO PINNEN, ALFREDO DI MURO, GIANCARLO ZANOTTI, GINO LUCENTE

Journal:

Chemical Biology & Drug Design

Year:

1987

Language:

english

File:

PDF, 641 KB

english, 1987

38

Ten-membered cyclotripeptides : Crystal structure and conformation of cyclo(-N-methylanthraniloyl-l-phenylalanyl-l-prolyl-)

SILVIO CERRINI, ENRICO GAVUZZO, GINO LUCENTE, FRANCESCO PINNEN

Journal:

Chemical Biology & Drug Design

Year:

1988

Language:

english

File:

PDF, 461 KB

english, 1988

39

Synthesis and Bioactivity of Secondary Metabolites from Marine Sponges Containing Dibrominated Indolic Systems

Mollica, Adriano, Locatelli, Marcello, Stefanucci, Azzurra, Pinnen, Francesco

Journal:

Year:

2012

Language:

english

File:

PDF, 293 KB

english, 2012

40

Synthesis of 1,2-Dithiolane Analogues of Leucine for Potential Use in Peptide Chemistry

Morera, Enrico, Pinnen, Francesco, Lucente, Gino

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

41

Approaches to pseudopeptidic ergopeptines. Synthesis and molecular structure of an ?-aza-phenylalanine-containing oxa-cyclol

Pinnen, Francesco, Luisi, Grazia, Lucente, Gino, Gavuzzo, Enrico, Cerrini, Silvio

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1993

Language:

english

File:

PDF, 779 KB

english, 1993

42

Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling

Alba Minelli, Silvia Grottelli, Annalisa Mierla, Francesco Pinnen, Ivana Cacciatore, Ilaria Bellezza

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

43

Phosphoproteomic analysis of the effect of cyclo-[His-Pro] dipeptide on PC12 cells

Alba Minelli, Ilaria Bellezza, Silvia Grottelli, Francesco Pinnen, Luigi Brunetti, Michele Vacca

Journal:

Year:

2006

Language:

english

File:

PDF, 396 KB

english, 2006

44

Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker

Mollica, Adriano, Costante, Roberto, Stefanucci, Azzurra, Pinnen, Francesco, Lucente, Gino, Fidanza, Stefano, Pieretti, Stefano

Journal:

Journal of Peptide Science

Year:

2013

Language:

english

File:

PDF, 290 KB

english, 2013

45

Hydantoin formation from alaninamide derivatives. Reactions with 5-amino-5-methylhydantoin

Giancarlo Zanotti, Francesco Pinnen

Journal:

Journal of Heterocyclic Chemistry

Year:

1981

Language:

english

File:

PDF, 430 KB

english, 1981

46

Conformationally Constrained Histidines in the Design of Peptidomimetics: Strategies for the χ-Space Control

Stefanucci, Azzurra, Pinnen, Francesco, Feliciani, Federica, Cacciatore, Ivana, Lucente, Gino, Mollica, Adriano

Journal:

International Journal of Molecular Sciences

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011

47

Biological Active Analogues of the Opioid Peptide Biphalin: Mixed α/β 3 -Peptides

Mollica, Adriano, Pinnen, Francesco, Costante, Roberto, Locatelli, Marcello, Stefanucci, Azzurra, Pieretti, Stefano, Davis, Peg, Lai, Josephine, Rankin, David, Porreca, Frank, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 713 KB

english, 2013

48

A Glutathione Derivative with Chelating and in vitro Neuroprotective Activities: Synthesis, Physicochemical Properties, and Biological Evaluation

Cacciatore, Ivana, Cornacchia, Catia, Fornasari, Erika, Baldassarre, Leonardo, Pinnen, Francesco, Sozio, Piera, Di Stefano, Antonio, Marinelli, Lisa, Dean, Annalisa, Fulle, Stefania, Di Filippo, Ester

Journal:

Year:

2013

Language:

english

File:

PDF, 604 KB

english, 2013

49

Hybrid peptides endomorphin-2/DAMGO: Design, synthesis and biological evaluation

Mollica, Adriano, Costante, Roberto, Stefanucci, Azzurra, Pinnen, Francesco, Luisi, Grazia, Pieretti, Stefano, Borsodi, Anna, Bojnik, Engin, Benyhe, Sándor

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 769 KB

english, 2013

50

Codrugs Linking l -Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease

Pinnen, Francesco, Cacciatore, Ivana, Cornacchia, Catia, Sozio, Piera, Cerasa, Laura Serafina, Iannitelli, Antonio, Nasuti, Cinzia, Cantalamessa, Franco, Sekar, Durairaj, Gabbianelli, Rosita, Falcioni

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

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